What Is Reglan?

Reglan, manufactured by the pharmaceutical company Schwarz Pharma, is the brand name for the drug metoclopramide. This prescription medication is used to treat stomach and intestinal problems, including:

  • Gastroesophageal reflux disease (GERD), a chronic digestive disease that results in stomach contents (acid and bile) flowing back into the esophagus, causing irritation of the esophagus (which typically manifests as acid reflux and heartburn);
  • Vomiting and nausea (such as that associated with chemotherapy, surgery, and migraine headaches); and
  • Gastroparesis (partial stomach paralysis that results in the stomach emptying itself of food irregularly), which is common among diabetics.

Metoclopramide, first developed in Europe in 1964, is a “dopamine antagonist”—something that blocks dopamine, a neurotransmitter. It works in the brain by blocking nausea messages (and, by extension, vomiting) as well as in the digestive system, where it accelerates food passage from the stomach to the intestine and also helps restore the gut’s normal muscle tone and function. In 1980, metoclopramide first gained FDA approval under the name Reglan, and it has been available in generic forms since 1982. Reglan can be taken as tablets or syrup, or by intravenous injection. Other brand names of the product include:

  • Maxolon
  • Degan
  • Maxeran
  • Primperan
  • Pylomid
  • Cerucal
  • Pramin

In February of 2009, the Food and Drug Administration (FDA) mandated a “black box” warning (its strongest warning) for Reglan and other medications that contain metoclopramide, due to the drug’s ability to cause tardive dyskinesia, an irreversible and untreatable disorder that causes involuntary and repetitive body movements. According to the FDA, more than two million Americans use metoclopramide products.

If you believe you have developed TD or have experienced any other adverse side effects as a result of taking taking Reglan, submit this simple secure form for a free and confidential evaluation of your eligibility to file a Reglan lawsuit.

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