Research shows the antidepressant duloxetine—sold under the brand name Cymbalta, Ariclaim, Xeristar, and Yentreve—causes suicidal thoughts and behaviors, heart-related side effects, and other complications. The Rottenstein Law Group compassionately advocates for those who have suffered from side effects as a result of having taken dangerous drugs. If you’ve taken Cymbalta and believe it harmed you, contact RLG for a free, confidential legal consultation immediately. We will evaluate your case and remain on the lookout for Cymbalta recalls and Cymbalta class action lawsuits. We might be the Cymbalta law firm you are looking for.
What Is Cymbalta and What Is Prescribed For?
Cymbalta is the brand name for the drug duloxetine. Made and sold by American pharmaceutical company Eli Lilly & Co., this prescription medication is used to treat major depressive disorder, generalized anxiety disorder, diabetic peripheral neuropathic pain, fibromyalgia, and chronic musculoskeletal pain. Eli Lilly failed to obtain clearance from the U.S. Food and Drug Administration (FDA) to sell Cymbalta as a treatment for stress urinary incontinence (SUI), though it did so in the European Union. Eli Lilly received approval to manufacture Cymbalta in August 2004, and does so in 20mg to 60mg delayed release oral capsules. Cymbalta made Eli Lilly $3 billion in revenue in 2009.
Cymbalta is a member of the Serotonin-Norepinephrine Reuptake Inhibitor (SNRI) class of antidepressants. Like Selective Serotonin Reuptake Inhibitors (SSRIs), SNRIs prevent receptors in the human brain from absorbing serotonin that has already been released. Serotonin helps people to maintain feelings of well-being, so preventing its re-absorption alleviates negative feelings. Unlike SSRIs, SNRIs also prevent re-absorption of norepinephrine (also called noradrenaline), which regulates stress levels. SNRIs take a few weeks to affect users, and they can cause many side-effects in the process, particularly nausea, somnolence, and sexual side-effects. It does not cause significant weight gain like SSRIs, though.
As the adverse effects of Cymbalta become better known, the FDA has required more stringent product warnings and prescription requirements, culminating with a 2006 “black box” Cymbalta warning. There is no effort to remove the product, and no Cymbalta recall is in effect. Meanwhile, concerns that antidepressants, including Cymbalta, are less effective than advertised are growing. For example, the New York Times reported that negative studies on their efficacy are often suppressed. The FDA also sent Wyeth a warning letter in 2007 over a Cymbalta advertisement in a medical journal that over-hyped its beneficial effects while downplaying the drug’s side effects.
Cymbalta Might Increase the Likelihood of Suicidal Thoughts and Other Side Effects
As early as 1990, people reported that antidepressants caused increased suicidal thoughts and behaviors. The FDA considered the issue, but it did nothing more. It became clear that antidepressants could adversely affect children and teenagers, making them hostile, irrational, violent, or suicidal. In 2006, the FDA analyzed the results of 372 studies of antidepressants, finding that even young adults (ages 18-25) were also afflicted with behavioral changes. As a result, the FDA ordered antidepressant manufacturers, including Eli Lilly for Cymbalta, to include added warnings to consumers.
Recently, a study conducted at Duke University concluded that those with coronary artery disease faced greater risk of death due to Cymbalta use. The researchers could not determine the reasons for the connection, but they found the connection statistically significant. For those with heart disease, in an average three years of follow-up, 21.4 percent of the participants still on antidepressants died as opposed to 12.5 percent who were not on antidepressants.
The “warnings and precautions” section of Cymbalta’s label warns that Cymbalta use can sometimes cause hepatic (liver) failure, which can be fatal. Liver failure is more likely in users who frequently drink alcohol or who already have chronic liver disease. Owing to these risks, the FDA chose against indicating Cymbalta for SUI.
RLG’s Lawyers Will Make Things Easier
The process of demanding compensation for the harm you have suffered can be complicated, even if it doesn’t seem fair that you should have to go through even more trouble to be made whole again. The lawyers at the Rottenstein Law Group believe that obtaining legal satisfaction from those who harmed you shouldn’t require more hardship. That’s why we do everything we can to streamline the process, and we will file a Cymbalta lawsuit on your behalf if necessary. RLG will also keep you up to date on any Cymbalta class action lawsuits, FDA Cymbalta warnings, and Cymbalta FDA recall announcements.
If you have taken Cymbalta and believe it harmed you, contact RLG today.