Research shows the antibiotic moxifloxacin—sold under the brand name Avelox or Avalox (or Avelon [oral solution] and Vigamox [eye drops])—causes liver disorders, Stevens-Johnson Syndrome and tendon injuries. The Rottenstein Law Group compassionately advocates for those who have suffered from side effects as a result of having taken dangerous drugs. If you’ve taken Avelox and believe it harmed you, contact RLG for a free, confidential legal consultation immediately. We will evaluate your case and remain on the lookout for Avelox recalls and Avelox class action lawsuits. We might be the Avelox law firm you are looking for.
What Is Avelox, and What Is It Prescribed For?
Avelox is a brand name for the drug moxifloxacin hydrochloride. Developed by German pharmaceutical giant Bayer AG, it is also marketed by Bayer’s partner Schering-Plough Corporation. This prescription medication is used to treat bacterial infections but only in limited circumstances after other antibiotics have failed. Avelox is a drug of last resort because it interacts with other drugs and even herbal supplements.
Bayer first patented moxifloxacin in 1991, but it took the FDA another eight years to approve the drug. Bayer intended it to replace ciprofloxacin. Avelox can be administered in three ways, most commonly by oral tablets containing 400mg of moxifloxacin. Another way is intravenous injection of 400mg moxifloxacin in 0.8% saline solution. Finally, Avelox can be administered in eye drops containing 5mg/mL of moxifloxacin. Due to its limited uses, Avelox can only be prescribed for chronic bronchitis, sinusitis, pneumonia and certain skin conditions.
Avelox is a broad-spectrum fluoroquinolone antibiotic, meaning it can be used against many different bacteria strains. Broad-spectrum antibiotics effectively combat undetermined life-threatening bacterial infections (such as meningitis) and symptoms caused by multiple concurrent bacterial infections. Avelox functions by disrupting DNA replication and cell division within bacteria. The drug is expensive and there are many cheaper and more effective antibiotics available.
Bayer depends on Avelox sales as the drug’s revenue in 2007 equaled $697.3 million worldwide, and it still earns roughly $500 million per year. Since it entered the market, though, controversies have eroded consumer confidence in Avelox. Consequently, in July 2008, the FDA placed a “Black Box” warning, the agency’s most serious alert, on Avelox. There are no known efforts to issue an Avelox recall or ban the drug. Though there are no serious Avelox lawsuits, the Rottenstein Law Group would like to hear from people who have used Avelox and experienced adverse effects.
Avelox Might Cause Life-Threatening Side Effects
In October 2008, the U.S. Food and Drug Administration (FDA) required Bayer to include a Black Box warning on packages to inform the public of side effects the drug causes. Avelox is known for causing liver disorders, and like many other fluoroquinolones, Avelox use correlates to muscle injuries, especially in tendons, the muscle tissue that binds muscles together. It can also cause a horrible life-threatening skin condition known as Stevens-Johnson Syndrome.
Bayer informed European doctors in “Dear Doctor” letters that Avelox could cause severe liver damage with symptoms including yellowing of the skin and eyes, severe itching, dark urine and pale-colored stool. The European Medicines Agency restricted Avelox’s uses. In March 2010, Canada followed.
The tendon problems caused by Avelox are not the results of new research. To the contrary, medical studies determined that existing fluoroquinolones caused muscle disorders back in the early 1970s. The FDA did not act quickly to issue an Avelox warning. In 2005 and 2006, a consumer advocacy group, Public Citizen, and the Attorney General of Illinois petitioned the FDA to require a Black Box warning on Avelox. In 2008, both petitioners finally sued the FDA to require the Avelox warning, and in October of that year it finally did so.
In August 2013, the FDA issued a drug safety communication advising the public that it was requiring a label-change to Avelox and other fluoroquinolone antibiotics to “better describe the serious side effect of peripheral neuropathy,” which is the medical term for potentially permanent nerve damage. Peripheral neuropathy can occur soon after Avelox treatment begins. It is associated with oral and injectable fluoroquinolones but not topical formulations of the drugs that are applied to the eyes and ears.
Some fear Avelox is over-prescribed and is now no longer effective because bacteria have developed resistances to it. Indeed, fluoroquinolones are among the most prescribed antibiotics in the United States, even though the FDA requires they be used only as a therapy of last resort. Frequently, they are even used for conditions for which they aren’t approved.
As of now, there are no known Avelox lawsuits or Avelox class action lawsuits, but they might well arise.
RLG’s Lawyers Will Make Things Easier
The process of demanding compensation for the harm you’ve suffered can be complicated, even if it doesn’t seem fair that you should have to go through even more trouble to be made whole again. The lawyers at the Rottenstein Law Group believe that obtaining legal satisfaction from those who harmed you shouldn’t require more hardship. That’s why we do everything we can to streamline the process, and we will file an Avelox lawsuit on your behalf if necessary. RLG will also keep you up to date on any Avelox class action lawsuits, FDA Avelox warnings and Avelox FDA recall announcements.
If you have taken Avelox and believe it harmed you, contact RLG today.