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Avelox Lawsuit

Research shows the antibiotic moxifloxacin—sold under the brand name Avelox or Avalox (or Avelon [oral solution] and Vigamox [eye drops])—causes liver disorders, Stevens-Johnson Syndrome and tendon injuries.

What Is Avelox? When Is It Prescribed?

Avelox is a brand name for the drug moxifloxacin hydrochloride. Developed by German pharmaceutical giant Bayer AG, it is also marketed by Bayer’s partner Schering-Plough Corporation. This prescription medication is used to treat bacterial infections, but only in limited circumstances after other antibiotics have failed. Avelox is a drug of last resort because it interacts with other drugs and even herbal supplements.

Bayer first patented moxifloxacin in 1991, but it took the FDA another eight years to approve the drug. Bayer intended it to replace ciprofloxacin. Avelox can be administered in three ways, most commonly by oral tablets containing 400mg of moxifloxacin. Another way is intravenous injection of 400mg moxifloxacin in 0.8% saline solution. Finally, Avelox can be administered in eye drops containing 5mg/mL of moxifloxacin. Due to its limited uses, Avelox can only be prescribed for chronic bronchitis, sinusitis, pneumonia, and certain skin conditions.

Avelox is a broad-spectrum fluoroquinolone antibiotic, meaning that it can be used against many different bacteria strains. Broad-spectrum antibiotics effectively combat undetermined life-threatening bacterial infections (such as meningitis) and symptoms caused by multiple concurrent bacterial infections. Avelox functions by disrupting DNA replication and cell division within bacteria. The drug is expensive and there are many cheaper and more effective antibiotics available.

Bayer’s Avelox sales revenue in 2007 was $697.3 million worldwide, and the drug still brings Bayer roughly $500 million per year. Since it entered the market, though, controversies have eroded consumer confidence in Avelox. In July 2008, the FDA placed a “black box” warning, the agency’s most serious alert, on Avelox, but there are no known efforts to effect an Avelox recall or to ban the drug.

Avelox Might Cause Life-Threatening Side Effects

In October 2008, the U.S. Food and Drug Administration (FDA) required Bayer to include a warning on Avelox packaging to inform the public of side effects the drug causes. Avelox is known to cause liver disorders, and like many other fluoroquinolones, Avelox use correlates to muscle injuries, especially in tendons, the tissues that binds muscles together. It can also cause a horrible life-threatening skin condition known as Stevens-Johnson Syndrome.

Bayer informed European doctors in “Dear Doctor” letters that Avelox could cause severe liver damage with symptoms including yellowing of the skin and eyes, severe itching, dark urine, and pale-colored stool. The European Medicines Agency restricted Avelox’s uses. In March 2010, Canada followed suit.

The tendon problems caused by Avelox were not only recently discovered. To the contrary, medical studies determined that existing fluoroquinolones caused muscle disorders back in the early 1970s. The FDA did not act quickly to issue an Avelox warning. In 2005 and 2006, a consumer advocacy group, Public Citizen, and the Attorney General of Illinois petitioned the FDA to require a black box warning on Avelox. In 2008, both petitioners finally sued the FDA to require the Avelox warning, and in October of that year it finally did so.

In August 2013, the FDA issued a drug safety communication advising the public that it was requiring a label change to Avelox and other fluoroquinolone antibiotics to “better describe the serious side effect of peripheral neuropathy,” which is the medical term for potentially permanent nerve damage. Peripheral neuropathy can occur soon after Avelox treatment begins. It is associated with oral and injectable fluoroquinolones but not topical formulations of the drugs that are applied to the eyes and ears.

Some fear that Avelox is over-prescribed and is now no longer effective because bacteria have developed resistances to it. Indeed, fluoroquinolones are among the most prescribed antibiotics in the United States, even though the FDA requires that they be used only as a therapy of last resort. Frequently, they are even used for conditions for which they aren’t approved.

RLG’s Lawyers Will Make Things Easier

The process of demanding compensation for the harm you’ve suffered can be complicated, even if it doesn’t seem fair that you should have to go through even more trouble to be made whole again. The lawyers at the Rottenstein Law Group believe that obtaining legal satisfaction from those who harmed you shouldn’t require more hardship. That’s why we do everything we can to streamline the process, and we will file an Avelox lawsuit on your behalf if necessary.

If you have taken Avelox and believe it harmed you, contact RLG today.

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rlg Previous Comments

  1. Guest
    on December 7, 2012 at 8:35 am

    My mother died while taking avelox in 11-4-11. She was fine before she took this med.

  2. Guest
    on August 27, 2012 at 6:34 pm

    Had tremors, anxiety, horrible fluctuating of blood glucose, insomnia, back pain, depressed thoughts, crying. I was being treated for pneumonia, after starting avelox, I started feeling so much worse. Felt like it was poisoning me! I had to set my clock every 2 to 2 1/2 hours to eat or I would have a sugar drop! Try doing that for 10 days straight around the clock, plus fight pneumonia! I've been off it 3 days and still have to eat more regularly and still some tremors and much anxiety! Help! When will I feel normal again? I am getting a liver function test this week at my recheck appointment! I also wanted to add after starting avelox my breathing felt harder. I felt like I was wearing a lead apron on my chest and back! Still have times it feels that way!

  3. Guest
    on August 4, 2012 at 10:44 am

    The drug has crippled me! In 2009, I was given Avelox IV in ER for pneumonia within minutes right Achilles tendon ruptured and swelled. Just had second perennial reconstruction surgery and probably will remain a cripple. The drug should be removed from the market!

  4. Guest
    on July 11, 2012 at 1:27 pm

    I took Avelox and had a severe reaction. My face and lips swelled horribly after about 7days. It has been about 4 1/2 months since I have taken Avelox. I have a rash that keeps recurring all over my body. I try to color my hair like I have been doing for years but everytime I do I react horribly to the all natural dye. My body is constantly itching. I used to have smooth skin. My skin currently looks like a mess. I have had a couple instances that I wake up at night. I've had a low fever and my body acts horribly. I take a couple advils and in the morning I seem fine. I can't find any solution to my problem.

  5. Guest
    on June 28, 2012 at 8:42 pm

    Last year I was given avelox for bronchitis. Side effects are muscle weakness, fatigue, could not get out of bed on my own. My boyfriend came to dr's appointment and let them know my symptoms. Experiencing myasthenia gravis symptoms. Went to many dr's and a lot of blood tests. Nothing showed up. But these symptoms had me out of work for almost 3 months. Today I still have muscle weakness in arms and legs. So, if there is going to be class action lawsuit I would like to be included. Thank you.

  6. Guest
    on June 2, 2012 at 2:45 am

    I was given Avelox and suffered a broken shoulder tendon and ruptured disc and now have major problems with achilles tendons. I also suffered major muscle loss in the neck and intestinal problems. I was never told this drug was dangerous, and I had only a mild infection.

  7. Guest
    on May 9, 2012 at 12:28 pm

    I was instructed to take Avelox as part of my IVF (invitro-fertilization) protocol. I was not even sick or had any infection. I was fine until I took amoxicillin in December of 2011. Five days after completing the amoxicillin I developed chest pain, insomnia, burning sensation in my skin (mainly my arms), neuropathy and paresthesias, dizziness and anxiety and depression. These are not common side effects of amoxicillin but are for Avelox. I truly feel the Avelox has caused some sort of alteration to my body physiology. I am concerned about a tendon rupture occurring as part of the protocol I followed had me take prednisone and Avelox together. I never knew such events could occur by taking these medications. I am truly scared to take any medication in the future. My life is very difficult now due to the dizziness, depression and general discomfort. I am very fortunate to have a loving and supportive husband.

  8. Guest
    on May 7, 2012 at 10:08 pm

    Avelox has caused a terrible wrist problem on me. I'm due to finish it tomorrow, and after I saw an ER doctor who told me that I had the worse wrist tendonitis he has ever seen, that can possibly leave me with permanent damage. I want that medication recalled and if I need surgery and treatments to regain the usage of my left hand, which I never had a problem with it, I will need the monetary compensation in order to do that... By the way, my infection got worse on Avelox.

  9. Guest
    on May 1, 2012 at 1:23 pm

    I was comatose 15 minutes after taking one avelox tablet. I have had continuous problems with my muscles and joints. Had a heart attack which I feel all stemmed from this drug. I have seen a lung specialist, ear nose throat doctor and a cardiologist. I have accumulated medical bills that are very costly.

    1. Guest
      on December 8, 2012 at 1:54 pm

      My husband had a heart attack about an hour after taking avelox and died in our dining room floor.

  10. Guest
    on February 25, 2012 at 4:58 pm

    I took Avalox for 7 days for a sinus infection six months ago, and I still have tendon pain throughout my body. I was very healthy and active before the medication, but now I cannot even take a walk without pain. Avalox should be taken off the market!

  11. Guest
    on February 8, 2012 at 5:41 pm

    I started having symptoms on January 7th and have been extremely ill since. Too many side effects to mention here. My doctor who had prescribed Avelox, now after ruling out a flu, says he thinks my symptoms could be an allergic reaction to the Avelox.

  12. Guest
    on February 2, 2012 at 8:20 pm

    I took one dose and could not tolerate the drug - it made me extremely nauseous, dizzy and racing heart. I was only able to hold it down for about 2 - 2/12 hours. Upon waking the next morning, I was unable to walk on my left leg. Extreme joint pain in the entire knee. I had loss of motion in the knee and no ability to bear weight. My Doctor changed meds immediately and the following day, I had no joint discomfort in my knee. I'm a healthy 48 year old female and feel that if this was possible with just one dose, it must be highly toxic to some. Very risky RX in my opinion.

  13. Guest
    on December 28, 2011 at 8:04 pm

    Went to the ER for severe allergic reaction (face swollen, airway closing, rash) from Avelox. Treated with large amounts of steroids and antihistamines. Instructed to never take this or any other related drug again. The Dr. said my outcome would have been worse if I had not taken a Zyrtec and diphenhydramine before bed that night.

  14. Guest
    on December 25, 2011 at 8:14 pm

    I took avelox for an ear infection back in April this year and I haven't been the same since. My left arm and neck still aches constantly and feels like pin and needles in it and itches. Of course, doctors say it's not the drug that's causing it. I have panic attacks on a regular basis and, recently, experienced sleep apnea. This drug is not the way to go.

  15. Guest
    on November 13, 2011 at 6:43 pm

    I had an allergic reaction and interaction with several drugs at the same time. I now have permanent peripheral neuropathy, damage to my autonomic nervous system, and trigeminal neuralgia. Avelox and cipro were given to me over a period of years for strep throat, bladder infections, and ear infections. I had a severe skin reaction but was taking so much benadryl I didn't go to the ER. I did call a doctor thinking it was another drug I had started. I am now allergic to a list of drugs along with permanent damage to my nervous system. I don't work at the present time, a result of the physical effects of the drug. My balance is affected and I am extremely heat intolerant and that affects my daily functioning to a frustrating extent. My life changed not long after the longest and largest prescription of Avelox. 10 days on 500mg for a very simple ear infection. Drug salesmen do not inform doctors of the problems with their new "wonder" drugs. And at that point in time, not enough is known about the future problems with the drug. I was a guinea pig and suffer greatly from those 10 days on the drug.

  16. Guest
    on November 1, 2011 at 12:40 pm

    I'm 32 going on 52 thanks to Avelox. I'm a big but (Was) a trim guy, and enjoy(ed) an active lifestyle with no prescription or recreation drug use. One year ago, I was given Avelox for the wrong reasons, a few days into use my entire body hurt from jaw to toe. My joints began to make cracks noises that people could hear in another room. As that subsided, the limitations did not. I still cannot run a mile every other day where I could run three miles flat any day, prior to this poison. I can't give my kids back rides, pick them up, or get down to play with them. Sitting hurts. Standing hurts. Sleeping hurts. I now have insomnia, depression, and trouble working well. Maybe I'm lucky I haven't ruptured a tendon, but I have damage that isn't ever going away. I want satisfaction. I want Avelox and all its siblings off the market. There is no way the FDA and doctors should allow this drug to be used on nearly everything, not sure if its appropriate for anything shy of prostate infections.

    The problem with this drug is it breaks some people, while others are bent. I could be wrong but legally the difference is massive. Does it make it okay for Bayer (etc.) to permanently and adversely harm people with this neglect? Someone please do something about this!

  17. Guest
    on September 21, 2011 at 5:09 pm

    Was prescribed 400mg avalox for 34 days. Having multiple side effects.

  18. Guest
    on August 4, 2011 at 7:27 pm

    I also took avelox for a severe ear infection about 3 months ago. I started having pain and pins and needles sensations in my left arm and shoulder a couple days after I started taking it. I also started having panic attacks quite frequently. Doctors keep telling me the two aren't related but I think they are, especially after reading others comments on other sites. My arm still hurts and bothers me and I still have panic attacks. I would never recommend this medicine to anyone. It should be taken off the market.

    1. Guest
      on August 13, 2011 at 7:23 am

      Sounds so much like what happened to my mom yesterday. She was given Avelox for a sinus infection within 40 minutes pins and needles sensation, skin on fire burning, hives from head to toe, and couldn't swallow, trouble breathing. She was rushed to urgent care 5 hours later stable enough to release her. It was so scary, and I am so angry reading all of these posting. There is no reason this drug should still be on the market.

  19. Guest
    on July 15, 2011 at 9:38 pm

    I am still suffering with nerve damage and tendonitis in both feet 5 months after taking just 3 pills. Initial symptoms were blurred vision, severe anxiety, uncontrolled muscle movements, inability to walk, etc. Tendonitis showed up a week after I stopped the pills. I am only 39 but am so limited in what I can do - more like a 79 year old. I filed a report with Medwatch (the FDA's reporting site). Many more people are going to have to report this drug before they will do anything. It is being prescribed like candy. Even the FDA has classified it as a drug of last resort. Why then was I given it as the first line of attack for acute (possibly even viral) bronchitis?

  20. Guest
    on July 14, 2011 at 6:01 am

    HAS ANYONE FILED A CLAIM ON AVELOX......THIS IS THE WORST DRUG. EVERY SIDE EFFECT WERE 1000 TIMES WORST THEN THE INFECTION THEY SAID I HAD.

  21. Guest
    on July 1, 2011 at 9:11 pm

    I was prescribed with Levaquin but the pharmacy said they don't keep Levaquin so they gave me Avelox. They said it was the same thing 10 pills, 10 days, 1 a day. I only took 2 days worth the first night, I woke up and my BP hit 150/97/100. An hour later, it went back down to 111/67/65. I had to lay on the floor and calm down. It felt like a Anxiety attack or something that happen to me both nights. 4 hours after taking the medicine, this is the 3rd day now and i have some pain on my left side. Could be my appendix, not sure, but I hope I caught it in time. I would not want anyone of any age have to go through what I did.

    All I was treated for was Sinusitis inner ear fluid infection.

    WARNING The Drug Avelox = Danger

  22. Guest
    on June 26, 2011 at 1:46 pm

    I was given Avelox around November 2009. After taking all of the medication, I began having tendonitis throughout various parts of my body. My Doctor kept insisting it was arthritis related, however every single X-ray and bloodwork for an arthritis profile was negative. I lost a lot of time from work, and even ended up in the emergency room because the pain and swelling was so bad. I am convinced this was all due to taking Avelox, there is no other explanation, and I am still experiencing frequent tendonitis issues in various parts of my body. Any help would be appreciated. Avelox is really bad medicine.

  23. Guest
    on May 28, 2011 at 7:34 pm

    I took a single Avelox pill. Within fifteen minutes, my air was cut off and I stopped breathing and my heart stopped. Through the help of a 911 operator, my wife was able to perform cpr. Between her, the emt's, and the grace of God, I am still here. This was not one of the side effects that was mentioned on the insert that came with the Avelox.

    1. Guest
      on July 3, 2011 at 4:41 pm

      I am very glad to know you survived the side effect of Avelox like I did. You are very correct about being able to breathe, I also had trouble breathing on that medicine and even more so when I went to bed I had to stay up everynight because it felt like my breathing would stop.

      I hope everything that we all went and are still going through that our voice on this website will reach Someone who can do something about this before it is too late.

  24. Guest
    on May 10, 2011 at 2:34 pm

    I've been seriously harmed by taking this medicine and it marked my life for ever.

  25. Guest
    on April 29, 2011 at 9:13 pm

    May 2, 2008 - my life changed forever. I took avelox for bronchitis and was facing a surgery on my hand. I took the first dose in the morning of my pre-op appointment and it was the first time I had ever been asked if I had been told my heart skipped a beat every once and awhile, nothing to worry about. The morning of my scheduled surgery I took the last dose and as I was being taken into the OR the nurse watched me go into rapid afib. No surgery and a 12 day admittance to the hospital the first time. I had a physical two months prior, as I had every year along with an EKG and never any heart problems. I was very active, exercised my whole life and was riding my bike 12 miles a day. Within two months avelox first hit my heart (causing numerous hospitalizations, cardio version and two cardiac ablations) nothing worked to put my heart into sinus rhythm. Then I went from normal kidney function to stage three kidney disease, I developed asthma and sleep apnea for the first time in my life and then my plasma cells were affected. All of this within two months of taking an antibiotic that should have never been approved by the FDA. Money talks. I will have kidney disease and problems with my plasma cells that require me to see a kidney specialist along with a hematologist/oncologist for the rest of my life. I will also have to see a pulmonary specialist and will have a higher risk of going back into afib. Bayer pharmaceutical and the FDA think only of money and nothing about the patients well being. Bayer knew about the ADR's and had the drug approved anyway. I place the blame on both of them. I feel very luck to be alive and try to spend my days without negativity in my life - however anything it takes to get Avelox off the market I am willing to do. No one should ever have their life changed so drastically from taking an antibiotic.

  26. Guest
    on April 20, 2011 at 9:52 am

    I was given Avelox 9 months ago, and although I haven't suffered a tendon rupture or liver problem yet, I have suffered many, many of the adverse side affects and have seen no less than 9 doctors and not one of them will agree that the Avelox caused these problems. Some of these physicians were very adamant and almost angry that I would even suggest that there precious drug destroyed my health. I am currently taking at least 8 drugs to try to calm my symptpms even though not one these doctors have tried to find out if my symptoms were caused by something else since they were sure the Avelox was not to blame. And the final knife in the back? I didn't even have a bacterial infection, it was viral.

    1. Guest
      on April 29, 2011 at 9:23 pm

      I was very fortunate I had a DR that believed me and actually took a book down and read the ADR's to me. He was the only one of the 8 Dr's that I was seeing, the rest are split on believing Avelox caused my problems. The rest are coming around slowly. However they did question each other about how such a healthy person could have all these things happen to them. I am so sorry that you are going through this and faith will help get you through. You will get better in time. Unfortunately it may take a long time . . . it was almost two years before I became stable and I thank God every that I survived and it's a good day.

  27. Guest
    on April 16, 2011 at 12:02 am

    Are you taking Avelox cases by any chance? I have had problems with this drug.

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