The U.S. Food and Drug Administration (FDA) has warned the public that the nuclear stress test agent adenosine—sold under the brand name Adenoscan—might cause heart attacks or death.
What Is Adenoscan? When Is It Prescribed?
Adenoscan is the brand name for the drug adenosine. Made and sold by Astellas Pharma US, Inc., the U.S. arm of the Japanese company Astellas Pharma, Inc., this prescription medication is used for cardiac nuclear stress tests. The FDA approved it as an intravenous injection in May 1995.
Doctors order cardiac stress tests for their patients to detect heart problems. Normally this is done by comparing the patient’s coronary circulation (circulation in the heart) at rest with the same circulation after exercising. The better the blood flow within the heart, the healthier the patient is overall.
Some patients who are incapable of exercise cannot undergo traditional stress tests. To test their coronary circulation, doctors must inject them with a compound like Adenoscan that dilates their blood vessels to help cardiologists detect obstructions with special imaging equipment.
Adenoscan Might Cause Heart-Attacks and Death
On November 20, 2013, the FDA issued a drug safety communication warning the public that it had received a substantial number of adverse event reports from or about patients who had been injected with Adenoscan and subsequently suffered heart attacks or death. From May 18, 1995, until April 10, 2013, the agency received six reports of myocardial infarction concerning patients injected with Adenoscan. Another 27 patients died under similar circumstances.
Not all the reports specified how long after the injection the adverse events occurred, but when it did appear the time was often within six hours of the injection. Another cardiac nuclear stress test agent, Lexiscan (regadenoson), also appeared in the report as causing injuries to patients. The FDA listed the following symptoms as common in patients who died after an Adenoscan injection:
- Cardiac arrest
- Myocardial infarction
- Loss of consciousness
- Respiratory arrest
- Electrocardiogram ST segment depression
- Pulmonary edema
- Ventricular fibrillation
As a result of the drug safety communication, the FDA mandated a change to Adenoscan’s drug label.
The agency believes that Adenoscan’s tendency to dilate blood vessels causes blood to flow to more open arteries. Arteries that are obstructed receive less blood, which can lead to fatal heart problems.
RLG’s Lawyers Will Make Things Easier
The process of demanding compensation for the harm you’ve suffered can be complicated, even if it doesn’t seem fair that you should have to go through even more trouble to be made whole again. The lawyers at the Rottenstein Law Group believe that obtaining legal satisfaction from those who harmed you shouldn’t require more hardship. That’s why we do everything we can to streamline the process, and we will file an Adenoscan lawsuit on your behalf if necessary.
If you or a loved one received an Adenoscan injection, and you believe it caused an injury, contact RLG today.